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Originating from modest roots in Andhra Pradesh, India, Dr. Sajja's journey epitomizes perseverance and commitment. He earned his MBBS from Guntur Medical College, followed by an MS in General Surgery from JIPMER, Pondicherry, and an M.Ch in Cardiothoracic and Vascular Surgery from AIIMS, New Delhi. His academic path led him to prestigious institutions, including advanced cardiovascular training at the Texas Heart Institute under Prof. Denton A Cooley. Dr. Sajja's influence in Cardiothoracic Surgery extends worldwide. As the founder of the Society of Coronary Surgeons, Dr. Sajja is committed to advancing coronary surgery in India. His leadership as Chairman of the Sajja Heart Foundation led to its recognition as a Scientific and Industrial Research Organization (SIRO) by the Government of India in 2019. Renowned for his innovative nature, Dr. Sajja's groundbreaking contributions to the field include pioneering the development of a mechanical prosthetic heart valve, holding patents in both the USA and India, thereby eliminating the need for long-term oral anticoagulation. Additionally, his design of the Mammary Artery Support Platform (MASP) has significantly improved surgical outcomes in CABG procedures. With an extensive background in over 21,000 open heart surgeries, Dr. Sajja leads multicenter randomized trials in Cardiac Surgery across India. His "PROMOTE Patency Study" garnered global recognition as India's first multicenter randomized controlled trial in cardiac surgery. Currently, he directs the "PREDICT Study" with backing from the Indian Council of Medical Research, New Delhi. Dr. Sajja's influence extends internationally through active participation in Multi-Centre International trials, contributing to global advancements in cardiac surgery. A member of prestigious international societies such as AATS, STS, EACTS, and ASCVS, Dr. Sajja has presented numerous original research papers at international conferences. His extensive publication record surpasses 110 original articles in peer-reviewed international journals. As the President of the Indian Association of Cardiovascular-Thoracic Surgeons (IACTS) from 2023-2024, Dr. Sajja continues to shape the future of cardiac surgery, benefiting patients worldwide. Dr. Lokeswara Rao Sajja's journey from a rural village to a pioneering Cardiothoracic Surgeon stands as a testament to his unwavering dedication, innovative spirit, and commitment to advancing cardiac care and research in India.