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In a groundbreaking medical achievement, doctors in China successfully transplanted a genetically engineered pig liver into a 71-year-old man suffering from terminal liver cancer. The surgery was performed at the First Affiliated Hospital of Anhui Medical University and marked a major step forward in xenotransplantation, the transplantation of animal organs into humans.

For the first 31 days after the operation, the pig liver functioned effectively, producing bile and blood-clotting proteins without signs of acute rejection. The pig’s liver was genetically modified with ten gene edits — three pig genes were removed to prevent immune rejection and seven human genes were added to improve compatibility.

However, after 38 days, complications arose due to the formation of blood clots in the liver’s small vessels. Despite receiving continuous medical support, the patient eventually succumbed to complications 171 days after the surgery.

Medical experts described the case as a significant milestone, proving that a gene-edited pig liver can sustain human life for an extended period. The achievement offers new hope for patients waiting for liver transplants and signals a major advancement in the global effort to address the shortage of human organ donors.