
Scientists in the United States are making big strides toward creating a universal cancer vaccine that could train the body’s immune system to fight different types of cancer. Research teams from the University of Florida, UCLA, and Brigham and Women’s Hospital are using mRNA technology, similar to the method used in COVID-19 vaccines, to develop this breakthrough treatment.
The vaccines work by introducing tumor-specific markers, called neoantigens, into the body. This helps the immune system produce special T-cells that can target and destroy cancer cells. In animal studies, these vaccines not only stopped tumors from growing but also removed tumors that were resistant to other treatments. One study even showed that mice had complete tumor removal along with stronger immune memory to prevent the disease from returning. Early human trials on a vaccine for KRAS mutations, linked to pancreatic and colorectal cancers, also showed longer survival and stronger immune responses.
Experts, however, caution that the idea of a “universal” vaccine is still in the early stages. Most successes so far have been in animal models or small human trials. More research is needed to confirm safety, dosage, and effectiveness across different types of cancer. While widespread use is still years away, scientists believe this progress marks a major step forward, raising hopes that a broadly effective cancer vaccine could become reality within the next decade.
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